Yesterday
• Real progress in organ transplantation began in 1954 with the first successful kidney transplant.
• During the 1960s, successful transplantation of pancreas/kidney, liver, isolated pancreas and heart occurred.
Today
• Tissue-engineered products are used to induce bone and tissue growth, guide long bone regeneration and replace damaged cartilage.
• Stem cells are available from a wide variety of sources. Animal and pilot human studies pave the way for clinical trials to treat many intractable diseases.
Tomorrow
• Materials Science meets Regenerative Medicine with “smart” biomaterials that actively formulate tissue.
• Novel techniques like removing organ cells and infusing new matter to the existing matrix to restore full functioning.
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Gene Therapy
The mission of our incubator is to accelerate gene therapy for human health and longevity.
We focus our work in three areas, click through to explore ongoing projects and meet the scientists.
How we are asking the big questions
The mission of our incubator is to accelerate gene therapy for human health and longevity.
We focus our work in three areas, click through the tabs below to explore ongoing projects and meet the scientists.
Gene therapy is the umbrella term for our work in rejuvenative medicine.How are skeletal tissues derived from skeletal stem cells? Here, we map bone, cartilage, and stromal development from a population of highly pure, postnatal skeletal stem cells (mouse skeletal stem cells, mSSCs) to their downstream progenitors of bone, cartilage, and stromal tissue. We then investigated the transcriptome of the stem/progenitor cells for unique gene-expression patterns that would indicate potential regulators of mSSC lineage commitment.
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Gene therapy is the umbrella term for our work in rejuvenative medicine.How are skeletal tissues derived from skeletal stem cells? Here, we map bone, cartilage, and stromal development from a population of highly pure, postnatal skeletal stem cells (mouse skeletal stem cells, mSSCs) to their downstream progenitors of bone, cartilage, and stromal tissue. We then investigated the transcriptome of the stem/progenitor cells for unique gene-expression patterns that would indicate potential regulators of mSSC lineage commitment.
Gene therapy is the umbrella term for our work in rejuvenative medicine.How are skeletal tissues derived from skeletal stem cells? Here, we map bone, cartilage, and stromal development from a population of highly pure, postnatal skeletal stem cells (mouse skeletal stem cells, mSSCs) to their downstream progenitors of bone, cartilage, and stromal tissue. We then investigated the transcriptome of the stem/progenitor cells for unique gene-expression patterns that would indicate potential regulators of mSSC lineage commitment.
Gene therapy is the umbrella term for our work in rejuvenative medicine.How are skeletal tissues derived from skeletal stem cells? Here, we map bone, cartilage, and stromal development from a population of highly pure, postnatal skeletal stem cells (mouse skeletal stem cells, mSSCs) to their downstream progenitors of bone, cartilage, and stromal tissue. We then investigated the transcriptome of the stem/progenitor cells for unique gene-expression patterns that would indicate potential regulators of mSSC lineage commitment.
International recognition
Coverage in top scientific journals
Updated regularly, here you will find a showcase of the team's major publications and previews of forthcoming projects.
Scroll down and click through the title links to view our top papers.
For a full catalogue of publications, please click here.
"Endochondral ossification is required for haematopoietic stem-cell niche formation."
Chan, C. K. et. al.
Nature
"Endochondral ossification is required for haematopoietic stem-cell niche formation."
Chan, C. K. et. al.
Cell
"Endochondral ossification is required for haematopoietic stem-cell niche formation."
Chan, C. K. et. al.
Science
Lab tour video
Enjoy a stroll around the Stanford campus in sunny Palo Alto, California and into our lab at the Lorry I. Lokey stem cell research building.
We are blessed to enjoy one of the best learning, research and living environments in the world.
The Lab Store
Crowd-sourced research?
Be a Friend of The Lab and become a rejuvenation philanthropist today.
Browse and purchase essential items for the lab.
Show your support by donating and receive an honour in return!
To discuss more extensive or ongoing support of our work, sponsorship and partner opportunities,
please reach out via the contact form below, or email rejuvenativemedicine@stanford.edu
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Accusamus numquam voluptatibus voluptatum eum distinctio non eum. Voluptatem qui delectus doloremque. Ut debitis officia necessitatibus et earum. Est libero autem ipsa ut neque ex esse. Nostrum maxime ut eos labore enim qui eos sed.
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Est quia quam temporibus dignissimos eos quo. Non iste soluta eveniet. Voluptatem ipsam ab a tempore doloribus aut. Maiores molestias eveniet dolorem incidunt sit itaque. Qui occaecati veritatis.
Accusamus numquam voluptatibus voluptatum eum distinctio non eum. Voluptatem qui delectus doloremque. Ut debitis officia necessitatibus et earum. Est libero autem ipsa ut neque ex esse. Nostrum maxime ut eos labore enim qui eos sed.
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Est quia quam temporibus dignissimos eos quo. Non iste soluta eveniet. Voluptatem ipsam ab a tempore doloribus aut. Maiores molestias eveniet dolorem incidunt sit itaque. Qui occaecati veritatis.
Accusamus numquam voluptatibus voluptatum eum distinctio non eum. Voluptatem qui delectus doloremque. Ut debitis officia necessitatibus et earum. Est libero autem ipsa ut neque ex esse. Nostrum maxime ut eos labore enim qui eos sed.
Iure Sed
Est quia quam temporibus dignissimos eos quo. Non iste soluta eveniet. Voluptatem ipsam ab a tempore doloribus aut. Maiores molestias eveniet dolorem incidunt sit itaque. Qui occaecati veritatis.
Accusamus numquam voluptatibus voluptatum eum distinctio non eum. Voluptatem qui delectus doloremque. Ut debitis officia necessitatibus et earum. Est libero autem ipsa ut neque ex esse. Nostrum maxime ut eos labore enim qui eos sed.
Iure Sed
Est quia quam temporibus dignissimos eos quo. Non iste soluta eveniet. Voluptatem ipsam ab a tempore doloribus aut. Maiores molestias eveniet dolorem incidunt sit itaque. Qui occaecati veritatis.
Accusamus numquam voluptatibus voluptatum eum distinctio non eum. Voluptatem qui delectus doloremque. Ut debitis officia necessitatibus et earum. Est libero autem ipsa ut neque ex esse. Nostrum maxime ut eos labore enim qui eos sed.
Iure Sed
Est quia quam temporibus dignissimos eos quo. Non iste soluta eveniet. Voluptatem ipsam ab a tempore doloribus aut. Maiores molestias eveniet dolorem incidunt sit itaque. Qui occaecati veritatis.
Accusamus numquam voluptatibus voluptatum eum distinctio non eum. Voluptatem qui delectus doloremque. Ut debitis officia necessitatibus et earum. Est libero autem ipsa ut neque ex esse. Nostrum maxime ut eos labore enim qui eos sed.
Iure Sed
Est quia quam temporibus dignissimos eos quo. Non iste soluta eveniet. Voluptatem ipsam ab a tempore doloribus aut. Maiores molestias eveniet dolorem incidunt sit itaque. Qui occaecati veritatis.
Accusamus numquam voluptatibus voluptatum eum distinctio non eum. Voluptatem qui delectus doloremque. Ut debitis officia necessitatibus et earum. Est libero autem ipsa ut neque ex esse. Nostrum maxime ut eos labore enim qui eos sed.
Partners
Explore our partner organisations
Donate
Every donation keeps the hands of time turning backwards! We value your support however little or large, the best way to join up with the mission in this way is by giving through the Stanford Stem Cell Institute.
Please follow the simple steps to make a secure donation at this link.
Careers
We are always interested to hear from potential collaborators, and driven scientists keen to join our project.
Please reach out with relevant information by email to chazchan@stanford.edu
Contact
Email: chazchan@stanford.edu
Address: Room G3, 3rd Floor, Lorry I. Lokey Stem Cell Research Building, 273 Campus Drive, Stanford, Palo Alto, California 9305, U.S.A.